Author Archives: Jim Zhe Zhang

About Jim Zhe Zhang

Principal Bioinformatics Scientist, PhD Department of Biomedical and Medical Informatics The Children's Hospital of Philadelphia

The Awsomics bioinformatics framework

Analysis of genomic data has become highly complicated, and a focus of modern biomedical research. Individual labs have growing needs to analyze different types of genomic data in a customized fashion to meet unique research goals. No matter the genomic … Continue reading

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Analysis of high dimensional data: a customized workflow

Genomic data are often high-dimensional. For example, a typical transcroptome data set has less than 100 samples, but over ten thousand genes/variables. This article will introduce a three-part workflow of analyzing high dimensional data: t-SNE for dimension reduction; dbSCAN for sample classificataion, and plotly for visualization. … Continue reading

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